The EB-5 infrastructure will allow the use of EB-5 funds for the operations of an online company as long as the required employment creation of 10 full time jobs per investor occurs.
If the business activities and, therefore, job creation, take place within a set geographical area, then the project could work. Of course, using an existing business for an EB-5 project has additional job creation requirements. If a direct EB-5 project, you can only count the actual full-time U.S. citizen or permanent resident employees of the company.